Intrathoracic carcinoma in an 11-year-old girl showing a translocation t(15;19). |
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| Authors: | U R Kees M T Mulcahy M L Willoughby |
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| Affiliation: | Department of Haematology-Oncology, Western Australian Research Institute for Child Health, Princess Margaret Hospital, Perth. |
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| Abstract: | We report here a rare case of intrathoracic undifferentiated carcinoma in an 11-year-old girl. The biopsy tissue stained with antibodies against cytokeratin and carcino-embryonic antigen. The same staining was obtained using a cell line, PER-403, which was derived from the tumor. DNA from PER-403 cells was tested for the presence of Epstein-Barr virus genes, yielding a negative result. The cytogenetic analysis found a translocation t(15;19) (p12;q13), which has not previously been described in a carcinoma. |
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