| 更昔洛韦并IVIG治疗HCMV婴儿肝炎综合征效果 |
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| 引用本文： | 宋宜娥,刘华林,刘瑞海.更昔洛韦并IVIG治疗HCMV婴儿肝炎综合征效果[J].齐鲁医学杂志,2006,21(5):417-418. |
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| 作者姓名： | 宋宜娥 刘华林 刘瑞海 |
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| 作者单位： | 1. 平邑县人民医院药剂科,山东,平邑,273300
2. 青岛市妇女儿童医疗保健中心内二科 |
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| 摘 要： | 目的探讨人巨细胞病毒(HCMV)婴儿肝炎综合征的有效治疗方案。方法选择2003~2005年住院的76例HCMV婴儿肝炎综合征病儿,随机分为两组。治疗组给予更昔洛韦(GCV)联合静脉用人血免疫球蛋白(IVIG)治疗;对照组单用GCV治疗。两组其他辅助治疗相同。结果治疗组肝功能恢复及病毒载量下降均较对照组明显(t=2.334~3.580,P<0.05)。结论GCV联合IVIG治疗HCMV婴儿肝炎综合征优于单用GCV。
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| 关 键 词： | 巨细胞病毒 婴儿 肝炎 更昔洛韦 免疫球蛋白类 |
| 文章编号： | 1008-0341(2006)05-0417-02 |
| 收稿时间： | 2006-02-16 |
| 修稿时间： | 2006-07-02 |
EFFECT OF GANCICLOVIR COMBINED WITH IVIG ON THE TREATMENT OF HCMV INFECTED INFANTILE HEPATITIS SYNDROME |
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| SONG YI-E,LIU HUA-LIN,LIU RUI-HAI.EFFECT OF GANCICLOVIR COMBINED WITH IVIG ON THE TREATMENT OF HCMV INFECTED INFANTILE HEPATITIS SYNDROME[J].Medical Journal of Qilu,2006,21(5):417-418. |
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| Authors: | SONG YI-E LIU HUA-LIN LIU RUI-HAI |
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| Abstract: | Objective To investigate the effective therapeutic protocol for infantile hepatitis syndrome(HIS) caused by human cytomegalovirus(HCMV).MethodsInfants with infantile hepatitis syndrome caused by HCMV(n=76) were divided into two groups.Treated group received ganciclovir(GCV) plus intravenous immunoglobulin(IVIG);control group received GCV only.ResultsThe patients in treated group had a better recovery of liver function and lower viral load than the patients in control group(t=2.334-3.580,P<0.05).ConclusionCombination of GCV with IVIG to treat infantile hepatitis syndrome caused by HCMV has better therapeutic effect than GCV alone. |
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| Keywords: | cytomegalovirus infant hepatitis ganciclovir immunoglobulins |
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