复方紫草油和高锰酸钾应用于肛瘘术后的作用对比研究

目的:对比观察复方紫草油和高锰酸钾用于肛瘘术后熏洗坐浴换药的疗效与安全性。方法:选取2015年1月至2017年7月上海交通大学第六人民医院收治的成功实施肛瘘切开术的低位单纯性肛瘘患者144例,按照随机数字表法分为对照组(高锰酸钾组)和观察组(复方紫草油组),每组72例。对比观察2组患者术后的疼痛评分,肛缘水肿评分,出血评分,分泌物消失所需时间,瘙痒改善所需时间,肉芽组织生长鲜活所需时间,术后感染发生率,住院时间,痊愈时间和不良事件。结果:观察者重度疼痛发生率和疼痛评分显著低于对照组(P0.05),肛缘水肿评分和出血评分显著低于对照组(P0.05),瘙痒症状改善,创面分泌物消失,创面肉芽组织到达鲜活状态所需时间显著短于对照组(P0.05),术后感染发生率显著低于对照组(P0.05),住院时间和痊愈时间显著短于对照组(P0.05),未发现药物相关不良反应。结论:肛瘘术后使用复方紫草油熏洗坐浴换药,有助于减轻术后疼痛、出血、肛缘水肿、继发感染等状况,促进术后创面愈合,从而缩短了痊愈所需时间和住院时间,并且安全性良好,值得推广使用。

Comparative Study on Fufang Zicao Oiling Agent and Potassium Permanganate after Anal Fistula Operation

To compare the efficacy and safety of FufangZicao Oiling agent and potassium permanganate after anal fistula operation.Methods:A total of 144 cases of simple anal fistula incision were selected and divided from Jan 2015 to Jul 2017 in the Sixth People''s Hospital of Shanghai Jiao Tong University into the control group (Potassium Permanganate group) and the observation group (FufangZicao Oiling agent group),with 72 cases in each group.The pain score,the anal margin edema score,the bleeding score,the time required for the disappearance of the secretions,the time required for the improvement of the pruritus,the time needed for the growth of the granulation tissue,the incidence of postoperative infection,the time of hospitalization,the recovery time and the adverse events were observed after the operation.Results:The incidence of severe pain and pain score of the observe group was significantly lower than that of the control group (P<0.05).The anal margin edema score and bleeding score were significantly lower than that of the control group (P<0.05).The time needed for The itching symptoms improved,the wound exudates disappeared and the wound granulation tissue reaching the fresh state was significantly shorter than the control group (P<0.05),and the incidence of postoperative infection was significantly lower than that in the control group (P<0.05),and the length of stay and recovery time were significantly shorter than those in the control group(P<0.05),and no drug related adverse reactions were found.Conclusion:The use of FufangZicao Oiling agent fumigation and bath dressing after anal fistula is helpful to relieve postoperative pain,bleeding,edema of the anal border,secondary infection and so on,and be helpful to promote the healing of postoperative wound,thus shortening the time needed of hospitalization,and the safety is well,that it is worth to be popularized.