| 肌动蛋白交联蛋白与血管内皮生长因子在肾细胞癌中的表达及其相关性 |
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| 引用本文： | 侯俊清,魏金星,常俊锴,李铁强.肌动蛋白交联蛋白与血管内皮生长因子在肾细胞癌中的表达及其相关性[J].中华实验外科杂志,2011,28(1):771-772. |
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| 作者姓名： | 侯俊清 魏金星 常俊锴 李铁强 |
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| 作者单位： | 450052,郑州大学第一附属医院泌尿外科;河南大学淮河医院泌尿外科;郑州大学第一附属医院泌尿外科,450052;河南大学淮河医院泌尿外科; |
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| 摘 要： | Objective To investigate the expression of Fascin and vascular endothelial growth factor (VEGF) in renal cell carcinoma (RCC) and the correlation with the biological behaviors. Methods The immunohistochemistry staining method was used to detect the expression of Fascin and VEGF in 92 cases of RCC and 20 cases of normal renal tissues as controls. Results The expression of Fascin in carcinoma tissue was significantly higher than that in normal tissues ( P ＜ 0. 05 ). Positive expression of Fascin and VEGF in renal cell carcinoma tissue was correlated with tumor grade ( P ＜ 0. 05 ) and clinical stage (P ＜0. 05 ) , but not with age, gender and different histological categories (P ＞ 0. 05 ). There was also a positive correlation between Fascin and VEGF (P ＜ 0. 05 ). Conclusion Fascin and VEGF are objective markers to estimate the behaviors of renal cell carcinoma.
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| 关 键 词： | 肾癌 肌动蛋白交联蛋白 血管内皮生长因子 生物学 |
Correlation of Fascin and vascular endothelial growth factor with the biological behaviors of renal cell carcinoma |
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| HOU Jun-qing,WEI Jin-xing,CHANG Jun-kai,LI Tie-qiang.Correlation of Fascin and vascular endothelial growth factor with the biological behaviors of renal cell carcinoma[J].Chinese Journal of Experimental Surgery,2011,28(1):771-772. |
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| Authors: | HOU Jun-qing WEI Jin-xing CHANG Jun-kai LI Tie-qiang |
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| Abstract: | |
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| Keywords: | Renal carcinomaFascinVEGFBiology |
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