Sensitivity and significance of nuclear magnetic tomography findings of finger joints in rheumatoid arthritis |
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Authors: | Peters R Ostendorf B Scherer A Becker A Dann P Merk H Mödder U Schneider M |
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Institution: | Klinik für Nephrologie und Rheumatologie Rheumazentrum Düsseldorf Heinrich-Heine-Universit?t Düsseldorf Moorenstr. 5, 40225 Düsseldorf, Germany. |
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Abstract: | Evaluation of the sensitivity and value of magnetic resonance imaging (MRI) findings and miniarthroscopic investigations (mini-/needle-arthroscopy = MA) of metacarpophalangeal (MCP) joints in patients with rheumatoid arthritis (RA). 30 patients with RA (21 female, 9 male), disease duration 2 months to 22 years and mean disease activity score (DAS) of 3.90 (range: 2.00-7.67) were examined by MRI of the hand (MCP region) and following MA of the MCP-II joints. MRI parameters for arthritis (synovial enhancement, synovial extension, cortical alterations, joint gap width) and corresponding macroscopic items (synovial extension, synovial hyperemia and vascularity, cortical alterations) by MA, scored semiquantitatively for synovitis (graduated from 0-III degree), were correlated. Additionally, normal radiographs of the hands were performed and compared with MRI findings concerning the detection of bony lesions. Evaluation of the 30 MRI and MA examination revealed highly significant correlations (p < 0.0001) for the parameters of synovial extension (MRI/MA), cortical alterations (MRI/MA) and synovial enhancement (MRI) compared to synovial hyperemia and vascularity (MA). We found significant correlations for parameters of activity and chronicity of RA pathology as assessed by MRI and MA. The detection rate of cortical lesions by MRI was two and a half times higher than by X-ray. MRI findings of MCP-II joints compared to those of MCP III-V showed that the MCP-II joint was more strongly involved. |
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Keywords: | Schlüsselw?rter Rheumatoide Arthritis MRT MCP-Gelenke Miniarthroskopie |
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