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Acquired von Willebrand syndrome in a patient with Ewing sarcoma
Authors:Elli Murat  Pinarli Faruk Guclu  Dagdemir Ayhan  Dabak Nevzat  Fisgin Tunc  Selcuk Mustafa Bekir  Sultansuyu Sevinc  Acar Sabri
Affiliation: a Department of Paediatric Oncology, Ondokuz Mayis University, Medical Faculty, Samsun, Turkeyb Department of Orthopaedics and Traumatology, Ondokuz Mayis University, Medical Faculty, Samsun, Turkeyc Department of Paediatric Haematology, Ondokuz Mayis University, Medical Faculty, Samsun, Turkeyd Department of Radiology, Ondokuz Mayis University, Medical Faculty, Samsun, Turkey
Abstract:Acquired von Willebrand syndrome is a rare bleeding disorder with clinical and laboratory features closely resembling to hereditary von Willebrand disease. The syndrome may accompany various conditions, including malignant disorders, most often with Wilms tumor and adrenal cell carcinoma. In this report, the authors present a patient with AvWS in association with Ewing sarcoma for the first time in the literature. The abnormal bleeding tendency was successfully treated with fresh frozen plasma and did not recur after the first two courses of chemotherapy with clinical improvement.
Keywords:acquired von Willebrand syndrome  Ewing sarcoma
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