急性脑梗死后抑郁病人甲状腺功能的研究

目的研究急性脑梗死抑郁病人的甲状腺功能变化规律.方法对89例急性脑梗死病人按抑郁评分结果进行分组,急性脑梗死抑郁组(A组)36例,急性脑梗死无抑郁组(B组)53例,于住院第7天采取血标本,按化学发光法测定甲状腺功能,并与30名健康者进行比较.结果 A组和B组血清游离三碘甲状腺原氨酸(FT3)水平与C组比较明显下降(P<0.01);A组和B组血清游离甲状腺素(FT4)水平明显高于C组(P<0.01).结论急性脑梗死抑郁病人甲状腺功能变化,表现为高FT4、低FT3.

Study on Thyroid Function in Depressed Patients after Acute Cerebral Infarction

Objective To study the change of thyroid function in the depressed patients after acute cerebral infarction.Methods 89 patients with acute cerebral infarction were divided into two groups:those with depression(n=36) and those without depression(n=53).Thyroid function (FT_3,FT_4,TSH) was tested by chemiluminescence method on the seventh day respectively after stroke and compared with normal control group.Results FT_3 was significantly decreased in the two groups compared with control group.FT_4 was significantly elevated in the two groups compared with the control group.FT_3 was significantly decreased but FT_4 was obviously elevated in patients with depression after acute cerebral infraction as compared without depression.Conclusion The thyroid function changes after acute cerebral infraction as high FT_4 FT_3 and high TSH in patients with depression after acute cerebral infarction.