Innovation in Urodynamics – Cystometry with Gas Perfused Catheters with Helium |
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| Institution: | 1. Department of Clinical Pharmacy, Meander Medical Center, Amersfoort, The Netherlands;2. Department of Pharmacy, Radboud Medical Center, Nijmegen, The Netherlands;3. Department of Nuclear Medicine, Meander Medical Center, Amersfoort, The Netherlands;4. Medical Radioisotope Program, Nuclear Security and Isotope Division, Oak Ridge National Laboratory (ORNL), Oak Ridge, TN, USA;5. Department of Internal Medicine/Medical Oncology, Meander Medical Center, Amersfoort, The Netherlands;6. Department of Clinical Pharmacology & Pharmacy, VU University Medical Center, Amsterdam, The Netherlands;7. Department of Medical Oncology, University Medical Center, Utrecht, The Netherlands;8. Department of Radiology & Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands;1. Trinity Centre for Digital Business, Trinity College Dublin, Dublin, Ireland;2. Department of Computer Science & Engineering, Amity School of Engineering & Technology, Amity University, Gurugram (Manesar), India |
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| Abstract: | PurposeProof of the fitness of the Gaserfusion method with helium for urodynamic studies on the basis of simultaneous comparative cystometries between Waterperfusion and Gasperfusion. Introduce gasperfusion to cystometry with children. Development of a combined measuring instrument for urodynamic and manometry of anorectum and esophagus.Material and MethodsPressure changes were measured with Gasperfusion in an artificial bladder in different positions and under movements. During 62 urodynamic investigations of 33 young patients between 5 months and 25 years 562 active (coughing) or passive (manual pressure at the bladder) provocation tests were performed. With the simultaneous measurement of the amplitudes of pressure changes in time in the bladder with two urethraly placed double channel catheters (6French), we get the velocity of pressure increase and could compare the common Waterperfusion with the new Gasperfusion using helium perfused catheters.ResultsIn the artificial bladder the pressure wasn`t changing either due to movement or different positions of the bladder. The Investigation of children shows the statistic significant higher velocities of pressure changes of the Gasperfusion than those measured with Waterperfusion.ConclusionsThe Gasperfusion has a lot of advantages for urodynamic investigations especially in children. The child can be measured in all possible body positions and during changing the body position. Helium is not dangerous for the human . The study with children showed better measuring results of the Gasperfusion especially in fast pressure changes like provocation and stress. We conclude that the Gasperfusion with helium is an excellent alternative to the common techniques using Waterperfusion and recommend the use of Gasperfusion in urodynamic studies espacially for children. Following these results it could be possible to have a new combination of equipment for measuring urodynamics and manometry of the gastrointestinal tract. |
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