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正交试验优选滋肾颗粒的提取工艺
引用本文:侯励,黄佩琨,李志国.正交试验优选滋肾颗粒的提取工艺[J].中药材,2005,28(5):423-425.
作者姓名:侯励  黄佩琨  李志国
作者单位:暨南大学附属第一医院,广州,510630
摘    要:目的:优选滋肾颗粒的提取工艺.方法:以浸膏得率和总蒽醌含量为指标,采用L9(3)4正交试验对滋肾颗粒的提取工艺进行优选.结果:最佳提取工艺为提取时间2 h、1.5 h,加水8倍量,提取2次,水溶液浓缩至相对密度1.10,加乙醇至含醇量为70%,静置24 h.结论:优选后的提取工艺、合理、稳定,适用于大生产.

关 键 词:滋肾颗粒  提取工艺  正交试验
修稿时间:2005年2月4日

Extracting Techniques for Optimizing Zi Shen Granule by Orthogonal Text
HOU Li,Huang Peikun,Li Zhiguo.Extracting Techniques for Optimizing Zi Shen Granule by Orthogonal Text[J].Jorunal of Chinese Medicinal Materials,2005,28(5):423-425.
Authors:HOU Li  Huang Peikun  Li Zhiguo
Institution:The First Affiliated Hospital of Jinan University, Guangzhou.
Abstract:Objective:To optimize the extracting techniques for Zi Shen Granule.Methods:By taking the rate of extractum and the total of anthraquinone as the indexes components,the extraction techniques were optimized for Zi Shen Granule through L 9(3)4 orthogonal text.Results:The best condition is twice extraction by 2h or 1.5h,to add octuple water.Then the water solution was concentrated to relative concentration 1.10,and adds ethanol to 70% alcohol Concentration,then stewing 24h.Conclusion:The optemized extraction technique is rational and jarless and ideal for mass production.
Keywords:Zi Shen Granule  Extraction technology  Orthogonal text  
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