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Favorable response of ADHD with giant SEP to extended-release valproate
Authors:Miyazaki Masahito  Ito Hiromichi  Saijo Takahiko  Mori Kenji  Kagami Shoji  Kuroda Yasuhiro
Affiliation:Department of Pediatrics, Institute of Health Biosciences, The University of Tokushima Graduate, Tokushima, Japan. mat@lilac.ocn.ne.jp
Abstract:We treated three boys with attention deficit/hyperactivity disorder (ADHD) associated with giant somatosensory evoked potentials (SEP). All responded well to extended-release valproate (EVA), a gamma-aminobutyric acid (GABA) enhancer. Improvement particularly involved hyperactivity and impulsivity. When methylphenidate previously was administered to two patients, symptoms worsened. EVA therefore may be preferable for ADHD with giant SEP.
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