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PTEN的研究进展及与乳腺癌的关系
引用本文:纪术峰,吴爱国.PTEN的研究进展及与乳腺癌的关系[J].中华肿瘤防治杂志,2004,11(8):876-879.
作者姓名:纪术峰  吴爱国
作者单位:第一军医大学珠江医院普外科,广东,广州,510282
摘    要:PTEN是 1997年发现的具有双重特异性磷酸酶活性的抑癌基因 ,该基因的变异与人类多种肿瘤的发生发展及预后有关。本研究就PTEN的研究进展及其与乳腺癌的关系进行了综述

关 键 词:PTEN  抑癌基因  乳腺癌
文章编号:1009-4571(2004)08-0876-04
修稿时间:2004年3月15日

Recent developments in the study of PTEN and its relation with breast cancer
JI Shu-feng,WU Ai-guo Zhujiang Hospetal,First Military Medical University,Guangzhou ,P.R.China.Recent developments in the study of PTEN and its relation with breast cancer[J].Chinese Journal of Cancer Prevention and Treatment,2004,11(8):876-879.
Authors:JI Shu-feng  WU Ai-guo Zhujiang Hospetal  First Military Medical University  Guangzhou  PRChina
Institution:JI Shu-feng,WU Ai-guo Zhujiang Hospetal,First Military Medical University,Guangzhou 510282,P.R.China
Abstract:PTEN discovered in 1997 is a tumor-suppressor gene with a dual-specificity phosphatase activity. PTEN is frequently mutated in a variety of human cancers,including breast cancers.Here,We plan to give a review about the recent developments in the study of PTEN and its relation with breast cancer.
Keywords:PTEN  tumor-suppressor gene  breast neoplasms
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