| 脑脊液腺苷脱氨酶测定对结核性脑膜炎的诊断意义 |
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| 引用本文： | 胡晓峰,孙淑红.脑脊液腺苷脱氨酶测定对结核性脑膜炎的诊断意义[J].医学检验与临床,2008,19(3). |
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| 作者姓名： | 胡晓峰 孙淑红 |
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| 作者单位： | 临沂市人民医院临检中心 |
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| 摘 要： | 目的探讨脑脊液腺昔脱氨酶(ADA)活性测定对结核性脑膜炎诊断的临床意义。方法对确诊的50例结核性脑膜炎、46例病毒性脑膜炎、42例化脓性脑膜炎及40例非脑炎患者采用LX20全自动生化分析仪检测脑脊液ADA活性。结果结核性脑膜炎患者组脑脊液ADA活性明显高于其它非结核性脑膜炎患者,平均为(12.69±5.08)U/L,最高达27.33U/L。病毒性脑膜炎、化脓性脑膜炎和其它非脑膜炎患者脑脊液ADA分别为(3.26±1.03)U/L(、4.52±2.11)U/L、(2.99±1.22)U/L,最高9.04U/L,与结核性脑膜炎患者相比差别有统计学意义(P<0.01)。结核性脑膜炎组43例患者治疗6周后脑脊液中ADA活性比刚入院时明显降低,差别有统计学意义(P<0.01)。结论脑脊液腺苷脱氨酶可作为诊断结核性脑膜炎的重要参考指标。
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| 关 键 词： | 结核性脑膜炎 腺苷脱氨酶 脑脊液 |
The Diagnosis Signifieance of Adenosthe Deaminase in the Cerebrospihal Fluid of Patients with Tuberculous Meningitis |
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| Hu Xiaofeng,Sun Shuhong.The Diagnosis Signifieance of Adenosthe Deaminase in the Cerebrospihal Fluid of Patients with Tuberculous Meningitis[J].Medical Laboratory Science and Clinics,2008,19(3). |
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| Authors: | Hu Xiaofeng Sun Shuhong |
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| Institution: | Hu Xiaofeng; Sun Shuhong(Clinical Laboratory Center of Linyi People s Hospital; Linyi; 276003); |
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| Abstract: | Objective To investigate the diagnosis significance of adenosine deaminase(ADA) in the cerebrospinal fluid of patients with tuberculous meningitis.Methods The activity of ADA in cerebrospinal fluid of 50 patients with tuberculous meningitis,46 patients with viral meningitis,42 patients with bacterial meningitis and 40 patients without encephalitis(as control) were determined with LX20 automatic biochemical analyzer.Results The level of cerebrospinal fluid ADA activity in patients with tuberculous meningitis... |
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| Keywords: | Tuberculous meningitis Adenosine deaminase Cerebrospinal fluid |
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