针刺配合卵细胞内单精子注射治疗自发性男性不育症

目的 :探讨针刺对自发性男性不育症患者施行卵细胞内单精子注射 (ICSI)治疗术临床疗效的影响。方法 :2 2例ICSI治疗失败的自发性男性不育症患者经过每周 2次、为期 2个月的针刺治疗后再次行ICSI治疗 ,观察治疗前后精液指标 ,ICSI治疗中的受精率。结果 :针刺治疗后快速活动精子的比率 ( 1 8 3± 9 6 % )高于治疗前 ( 1 1 0± 7 5% ) ,差异极为显著 (P <0 0 5)。治疗后正常形态的精子所占的比率 ( 2 1 1± 1 0 4% )亦显著高于治疗前 ( 1 6 2± 8 2 % ,P <0 0 5)。针刺治疗后行ICSI治疗的受精率 ( 6 6 2 % )明显高于治疗前 ( 40 2 % ,P <0 0 1 )。治疗前后精子的浓度和总的精子活动率没有显著性的差异。结论 :针刺能使自发性男性不育症患者的精子质量提高 ,从而达到提高ICSI治疗中受精率的目的

Treatment of Idiopathic Male Infertility by Acupuncture Combined with Intracytoplasmic Injection of Sperm

Objective:To investigate the clinic effect of acupuncture on idiopathic male infertility in accepting intracytoplasmic sperm injection (ICSI).Methods:Twenty-two cases of idiopathic male infertility patients failed in ICSI were treated with acupuncture twice weekly for 8 weeks, and then followed by accepting ICSI treatment again. Acupoints used were Baihui (GV 20), Neiguan (PC 6), Chize (LU 5), Xuehai (SP 10), Neiting (ST 44), Shenshu (BL 23), Sanyinjiao (SP 6), Qihai (CV 6), Guanyuan (CV 4), etc. Within 3 months after acupuncture treatment, the patients accepted ICSI treatment again. The sperm concentration, motility, morphology and fertility rates were observed.Results: Sperm quick motility after acupuncture treatment (18.3±9.6%) was significantly improved than that before acupuncture (11.0±7.5%, P<0.05). The normal sperm ratio was increased after acupuncture(21.1±10.4% vs 16.2± 8.2%,P<0.05). The fertility rates after acupuncture (66.2%) were obviously higher than that before acupuncture (40.2%,P<0.01). There was no significant difference in sperm concentration and general sperm motility before and after acupuncture. But among their spouses, 4 cases had been affirmed to be gravid, with the pregnancy rate being 18.2%.Conclusion:Acupuncture can improve infertility patients' sperm quality and raise fertility rate during accepting ICSI treatment.