长沙社区50岁以上人群卒中危险因素和脑血管血流动力学积分的关系

目的 研究长沙市社区50岁以上城市居民卒中危险因素和脑血管血流动力学积分的关系。方法 2008年在长沙市进行50岁以上社区居民的随机抽样，进行卒中常见危险因素（包括高血压、糖尿病、心脏病、高血脂、吸烟、饮酒）的基线调查，同时进行脑血管血流动力学指标（cerebralvascular hemodynamics index，CVHI）检测，并对检测结果进行综合积分。根据有无卒中危险因素将队列人群分为对照组、单一危险因素和多个危险因素组。研究卒中危险因素与CVHI积分的关系。结果 （1）与对照组比较，高血压组和多个危险因素组的CVHI积分明显下降，差异具有统计学意义（P均<0.01）；高血压组和多个危险因素组中高危人群（CVHI积分50～75分）和极高危人群（CVHI积分≤50分）所占比例高于对照组，差异有统计学意义（P均<0.01）。（2）随着危险因素暴露的增加，CVHI积分呈下降趋势，高危人群和极高危人群所占比例呈增高趋势，差异有统计学意义（P <0.01）。结论 高血压病史和多个危险因素的聚集会明显降低脑血管血流动力学积分。

Relationship between Risk Factors of Stroke and Cerebrovascular Hemodynamics Indexes Score in Urban Population Aged above 50 in Changsha

Objective To probe into the relationship between cerebral vascular hemodynamicsindexes （CVHI） accumulative score and risk factors of stroke in urban population aged above 50 in Changsha. Methods Residents aged above 50 in changsha urban were selected randomly to spot-check in 2008. In the baseline survey, the risk factors of stroke, such as hypertension, diabetes, cardiac disease, hyperlipemia, smoking and drinking were collected and CVHI were examined. CVH1 accumulative score was synthesized according to contribution of single index. According to whether with any risk factors, the subjects were divided into the control group,the single risk factor group and the multiple risk factors group. We study the relationship between the stroke risk factors and CVHI accumulative score. Results （l）Compared with the control group, scores of CVH! score in the hypertension and the multiple risk factors group were significantly decreased（P〈0.01）. And the rates of high-risk groups whose score bellowed 75 points and the very high-risk groups whose score bellowed 50 points in the hypertension group and the multiple risk factors group were more higher than those in the control group, the differences were significant（P〈0.01）. （2）With the increase of risk factors, the scores of CVHI were decreased and the rates of high-risk groups and the very high-risk groups were increased respectively（P〈0.01）. Conclusion CVHI score would significantly reduce with hypertension and multiple risk factors.