SCA2 and SCA3 mutations in young-onset dopa-responsive parkinsonism |
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| Authors: | M. Svetel,A. Djarmati,N. Draga&# evi&# ,D. Savi&# ,B. &# uljkovi&# ,S. Romac, V. S. Kosti&# |
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| Affiliation: | Institute of Neurology CCS, School of Medicine, University of Belgrade, Belgrade, Serbia;;and
PCR Center, Faculty for Biology, University of Belgrade, Belgrade, Serbia |
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| Abstract: | In this study no one of our 85 patients of Serbian origin with young-onset (≤ 45 years) dopa-responsive parkinsonism (YOP), previously proved negative for PARK1 and PARK2 mutations, had either spinocerebellar ataxia type 2 (SCA2) or SCA3 mutation. These data do not prove the significance of these two mutations in either sporadic or familial YOP suggestive of Parkinson's disease. |
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| Keywords: | SCA2 SCA3 young-onset parkinsonism |
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