| 感染性疾病与人类基因组研究进展 |
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| 引用本文： | 李东良. 感染性疾病与人类基因组研究进展[J]. 国际流行病学传染病学杂志, 2004, 36(1): 188-192. DOI: 10.3760/cma.j.issn.1673-4149.2009.03.016 |
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| 作者姓名： | 李东良 |
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| 作者单位： | 南京军区福州总医院肝胆病中心肝胆内科,350025; |
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| 摘 要： | 病原体感染后,机体对其清除能力以及疾病的转归,在很大程度上取决于个体间基因组的差异.研究发现,人类白细胞抗原(HLA)、细胞因子(CK)、甘露糖结合蛋白(MBL)、维生素D受体(VDR)、红细胞抗原等基因与感染性疾病的易感性有关.此文就近年来该研究领域的进展作了综述.
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| 关 键 词： | 感染性疾病 基因多态性 人类基因组 |
Advances on research of infectious diseases and human genome |
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| LI Dong-liang. Advances on research of infectious diseases and human genome[J]. International Journal of Epidemiology and Infectious Disease, 2004, 36(1): 188-192. DOI: 10.3760/cma.j.issn.1673-4149.2009.03.016 |
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| Authors: | LI Dong-liang |
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| Abstract: | When a person gets infections, the ability of pathogenic cleaning and the disease outcome largely depend on the individual genome.h is found that HLA, CK, MBL,VDR and red cell antigens are relative to infectious disease susceptibility. In this paper, the progress in this field is reviewed. |
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| Keywords: | Infectious diseasesGene polymorphismHuman genome |
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