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IgA肾病血瘀证与肾脏病理损害的关系研究
引用本文:王丽萍,陈建,庄永泽,陈锦华,姚丽青,郑智勇,陈香美.IgA肾病血瘀证与肾脏病理损害的关系研究[J].中国中医药信息杂志,2008,15(1):21-23.
作者姓名:王丽萍  陈建  庄永泽  陈锦华  姚丽青  郑智勇  陈香美
作者单位:1. 中国人民解放军南京军区福州总医院,福建,福州,350025
2. 中国人民解放军总医院,北京,100853
摘    要:目的研究IgA肾病血瘀证与临床病理的相关因素。方法分析42例IgA肾病血瘀证与73例非血瘀证患者的临床及肾脏病理资料。结果IgA肾病血瘀证临床上合并肾功能不全多见,血瘀证女性多见;血瘀证组Lee分级重于非血瘀证组;血瘀证组肾组织纤维蛋白原相关抗原沉积程度明显强于非血瘀证组:血瘀证组肾小管萎缩积分或肾小管萎缩比例明显高于非血瘀证组。结论血瘀证与IgA肾病肾组织病理有一定相关性,血瘀是IgA肾病肾功能恶化的主要致病因素。

关 键 词:IGA肾病  中医辨证  血瘀证
文章编号:1005-5304(2008)01-0021-03
收稿时间:2007-04-27
修稿时间:2007年4月27日

Study on the Relationship between Blood Stasis Syndrome and Clinical Pathology in IgA Nephropathy Patients
WANG Li-ping, CHEN Jian, ZHUANG Yong-ze, et al.Study on the Relationship between Blood Stasis Syndrome and Clinical Pathology in IgA Nephropathy Patients[J].Chinese Journal of Information on Traditional Chinese Medicine,2008,15(1):21-23.
Authors:WANG Li-ping  CHEN Jian  ZHUANG Yong-ze  
Institution:WANG Li-ping, CHEN Jian, ZHUANG Yong-ze, et al (Fuzhou General Hospital of Nanjing Military Region, Fuzhou 350025, China)
Abstract:Objective To observe the relationship between blood stasis syndrome and clinical pathology in patients with IgA nephropathy (IgAN). Methods Clinical and pathological materials of 42 patients with blood stasis syndrome, and 73 patients with non blood stasis syndrome were analyzed. Result Patients with blood stasis syndrome are often female and accompanied with renal dysfunction. Compared with patients of non blood stasis syndrome, Lee's grades were obviously higher, degrees of fibrinogen-related antigen (FRA) deposited in renal were stronger, and scores or ratio of tubular atrophy significantly were higher. Conclusion Blood stasis syndrome of IgAN is correlated with certain renal pathological changes. Blood stasis is the main etiological factor.
Keywords:IgA nephropathy  blood stasis syndrome  syndrome diferentiation of TCM
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