中医分型辨治颈动脉硬化85例

目的观察中医分型辨治颈动脉硬化的临床疗效。方法将116例颈动脉硬化病例分为治疗组85例和对照组31例。治疗组中肾虚型(31例)、血瘀型(20例)和痰湿型(34例)患者分别给予软脉煎、脉血康胶囊、六君子汤加减治疗,对照组予辛伐他汀;各组疗程均为24周,观察治疗前后颈动脉斑块和内膜中层厚度及血脂的变化情况。结果治疗组、对照组颈动脉斑块、内膜中层厚度疗效差异无统计学意义(P>0.05),两组间血脂疗效差异有统计学意义(P<0.05)。结论中医分型辨治颈动脉硬化与辛伐他汀治疗比较,疗效相当。

Differentiation and treatment of carotid atherosclerosis in different patterns with Chinese Medicine:A report of 85 cases

Objective To observe the clinical efficacy of carotid atherosclerosis differentiated and treated with Chinese Medicine.Methods One hundred and sixteen cases were divided into treatment group and control group.Thirty cases in control group were treated with simvastatin and 85 cases in treatment group were divided into three patterns:kidney deficiency pattern,blood stasis pattern and phlegm damp pattern,these three patterns were treated with proven "Ruanmai Decotion","Maixuekang Capsule" and modified "Liujunzi Decoction" respectively,with a course of 24 weeks.The carotid plexus,intima media thickness and blood lipids were observed before and after treatment.Results No significant difference was found in effects of carotid plexus and intima media thickness between the treatment group and the control group(P>0.05),while there was difference in effect of blood lipids(P<0.05).Conclusion Differentiation and treatment of carotid atherosclerosis in different patterns with TCM provide a similar therapeutic effect to simvastatin.