Central depressant drugs. 2. 3-Substituted 4-hydroxypyrimido[1,2-a]benzimidazol-2-ones

Centrally Dampening Drugs, II: 3-Substituted 4-Hydroxypyrimido[1,2-a]benzimidazol-2-ones The 4-hydroxypyrimido[1,2-a]benzimidazol-2-ones 3a–g obtained by reacting 2-aminobenzimidazole (1) with the malonic acid esters 2a–g exhibit centrally dampening, hypertensive, fungicidal, and antibacterial properties.