| 2型糖尿病患者补体调节蛋白CD55、CD59水平的变化及其意义 |
| |
| 引用本文： | 马西文,刘永铭,赵丽,薛芙珍,尚东亚. 2型糖尿病患者补体调节蛋白CD55、CD59水平的变化及其意义[J]. 中华糖尿病杂志, 2007, 15(12): 740-741 |
| |
| 作者姓名： | 马西文 刘永铭 赵丽 薛芙珍 尚东亚 |
| |
| 作者单位： | 兰州大学第一医院老年病科,730000 |
| |
| 摘 要： | 选2型糖尿病患者33例，24名健康自愿者作为对照，检测外周血白细胞CD55、CD59的表达．探讨其与糖尿病肾病的关系。2型糖尿病患者CD55、CD59表达下词，糖尿病病程、CD55阳性单核细胞平均荧光强度是尿白蛋白排泄率（UAER）的独立预测因素。补体调节蛋白表达减低可能与糖尿病肾病的发生有关。
|
| 关 键 词： | 2型糖尿病 尿白蛋白排泄率 补体调节蛋白 |
| 收稿时间： | 2005-11-09 |
| 修稿时间： | 2005-11-09 |
The expression changes of complement regulatory proteins CD55,CD59 in type 2 diabetes and their implication |
| |
| MA Xi-wen ,LIU Yong-ming , ZHAO Li ,et al.. The expression changes of complement regulatory proteins CD55,CD59 in type 2 diabetes and their implication[J]. CHINESE JOURNAL OF DIABETES MELLITUS, 2007, 15(12): 740-741 |
| |
| Authors: | MA Xi-wen LIU Yong-ming ZHAO Li et al. |
| |
| Affiliation: | MA Xi-wen ,LIU Yong-ming , ZHAO Li , et al. |
| |
| Abstract: | To investigate the relationship between complement regulatory proteins and diabetic nephropathy, the expressions of CD55, CD59 on circulating leukocytes were examined in 33 patients with type 2 diabetes mellitus and in 24 healthy volunteers served as controls. The expressions of CD55, CD59 in type 2 diabetics were down-regulated. The diabetic course and mean fluorescence intensity of CD55-positive monocytes were the independent predictors of urine albumin excretion rate. The down-regulation of complement regulatory proteins might involve in the pathogenesis of chronic diabetic nephropathy |
| |
| Keywords: | Diabetes mellitus, type 2 Urine albumin excretion rate Complement regulatory protein |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
