| 万克灵消毒剂的毒理试验 |
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| 引用本文： | 陈湘宜,左丹,宗润芝,付军,朱光奇. 万克灵消毒剂的毒理试验[J]. 泸州医学院学报, 2001, 24(3): 189-191 |
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| 作者姓名： | 陈湘宜 左丹 宗润芝 付军 朱光奇 |
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| 作者单位： | 武汉大学医学院流行病学教研室, |
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| 摘 要： | 目的：研究万克灵的毒性作用。方法：经口、粘膜、皮肤试验。结果：小鼠经口毒性试验未显示毒性。该消毒剂对家兔皮肤无刺激性，对家兔眼结膜有轻度刺激反应，50%万克灵消毒剂（甘油稀释）则属无刺激性。对豚鼠皮肤致敏变态反应阴性，对小鼠骨髓细胞染色体无效突变作用。结论：经毒理试验显示万克灵消毒剂是一种应用于室内空气安全可靠的消毒剂。
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| 关 键 词： | 臭氧化物 LD50 致突变 万克灵消毒剂 毒理试验 |
| 文章编号： | 1000-2669(2001)03-0189-03 |
| 修稿时间： | 2000-12-04 |
TOXICOLOGICAL ASSAY FOR DISINFECTANT WAN KE LING |
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| Chen Xiangyi,et al The. TOXICOLOGICAL ASSAY FOR DISINFECTANT WAN KE LING[J]. Journal of Luzhou Medical College, 2001, 24(3): 189-191 |
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| Authors: | Chen Xiangyi et al The |
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| Affiliation: | Chen Xiangyi,et al The Department of Epidemiology,Medical School,Wuhan University |
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| Abstract: | Objective: To determine the toxicity of Wan Ke Ling. Methods: Toxicological tests per os through skin and mucosa were performed. Results:Toxicological assay of Wankeling per os showed no toxicity. The disinfectant didn't show stimulation on skin of rabbits, but showed slight stimulation on conjunctiva of rabbits. 50% Wan Ke Ling diluted with glycerol showed no stimulation. Allergy of skin of guinea pig was negative. There was no aberration of chromosome of bone marrow of mice. Conclusion: Toxicological assay indicates that Wan Ke Ling is a safe and highly effective disinfectant for indoor air. |
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| Keywords: | Ozonide LD 50 Aberration |
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