Influence of Brain-activating Acupuncture on Cerebral Histomorphology in Rats with Focal Cerebral Ischemia and Reperfusion |
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| Authors: | Wang Shu Wang Zhan-kui Ni Guang-xia |
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| Institution: | (1) Geriatric Research Institute, First Hospital Affiliated to Tianjing College of Traditional Chinese Medicine, 300193 Tianjing, P. R. China;(2) Acupuncture and Moxibustion Department, Second Hospital Affiliated to Tianjing College of Traditional Chinese Medicine, 300193 Tianjing, P. R. China;(3) First Hospital Affiliated to Tianjing College of Traditional Chinese Medicine, 300193 Tianjing, P. R. China |
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| Abstract: | Objective: To investigate the pathological changes following the focal cerebral ischemia and reperfusion in rats and the effect of
acupuncture on them.Methods: A model of ischemia and reperfusion was established by thread occlusion, and the brain-activating acupuncture was applied,
and then the morphological changes of the cerebral cortex on the ischemic side were observed under electron and light microscopes.Results: Cerebral ischemia and reperfusion could lead to the structural injury of neurons, gliacytes and capillary vessels in rat’s
brain, and acupuncture could improve the ultra-structural injury in the area around the cerebral ischemia. It was also found
that acupuncture intervention at 3 hours following reperfusion was more ideal than that at any other time points.Conclusion: Acupuncture has a protective effect on the ultra-structural injury of neurons associated with focal cerebral ischemia and
reperfusion in rats, and acupuncture given within 3 hours following reperfusion can produce a satisfactory effect.
Author: WANG Shu (1965-), male, professor and chief physician, engaged in the clinical and basic research of cerebrovascular diseases
Translator: ZHU Zhong-chun |
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| Keywords: | Cerebral Ischemia and Reperfusion Morphology Acupuncture |
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