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PRK术后屈光回退和Haze的药物防治进展
引用本文:房城伯. PRK术后屈光回退和Haze的药物防治进展[J]. 现代诊断与治疗, 2003, 14(4): 239-241
作者姓名:房城伯
作者单位:安徽医科大学第一附属医院眼科,安徽,合肥,230022
摘    要:就近年来准分子激光屈光性角膜切削术 (PRK )后屈光回退和角膜上皮下雾状混浊 (Haze)两大并发症的药物防治进展作一简要综述。阐述了局部应用皮质类固醇药物、非甾体抗炎药物、抗代谢药物、抗氧化剂、Caspase抑制剂、细胞因子调控、锌制剂对减弱角膜创伤愈合反应 ,阻断或减少角膜细胞凋亡的作用 ,从而预防和治疗屈光回退和Haze形成 ,提高PRK手术的稳定性和预测性。

关 键 词:准分子激光屈光性角膜切削术  屈光不正  角膜混浊
文章编号:1001-8174(2003)04-0239-02
修稿时间:2003-03-03

Progress in Medicinal Prevention and Treatment of Regression and Haze after Photorefractive Keratectomy
FANG Cheng-bo. Progress in Medicinal Prevention and Treatment of Regression and Haze after Photorefractive Keratectomy[J]. Modern Diagnosis & Treatment, 2003, 14(4): 239-241
Authors:FANG Cheng-bo
Abstract:The latest progress in medicinal prevention and treatment of regression and haze,which are major complications after photorefractive keratectomy(PRK),is concisely elucidated.We explained the effects of local application of corticosteriod,non-steroid antiinflammatory immunity drugs(NSAIDs),antimetabolism drugs,antioxidants,caspase inhibitors,cytokine mediators and Znic to weaken the healing reaction of corneal trauma,block or reduce corneal apoptosis,which can prevent and treat corneal regression and haze after photorefractive keratectomy,and raise the stability and prediction of PRK.
Keywords:Photorefractive keratectomy  Refractive errors  Corneal opacity
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