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咪唑斯汀联合白芍总苷胶囊治疗慢性特发性荨麻疹临床疗效观察
引用本文:王军,马小玲,刘雯蓓,慈超,常小丽,季必华.咪唑斯汀联合白芍总苷胶囊治疗慢性特发性荨麻疹临床疗效观察[J].中国临床药理学与治疗学,2010,15(1):98-101.
作者姓名:王军  马小玲  刘雯蓓  慈超  常小丽  季必华
作者单位:1. 皖南医学院弋矶山医院皮肤科,芜湖,241001,安徽
2. 南京市妇幼保健院皮肤科,南京,210004,江苏
基金项目:皖南医学院弋矾山医院中青年骨干医师基金 
摘    要:目的:观察咪唑斯汀联合口服白芍总苷胶囊治疗慢性特发性荨麻疹的疗效。方法:选择120例慢性特发性荨麻疹患者,按就诊顺序分为两组,治疗组给予咪唑斯汀联合口服白芍总苷胶囊,对照组单一给予咪唑斯汀。结果:治疗结束时治疗组有效率为88%,对照组有效率为87%,两者之间差异无统计学意义;治疗结束后3个月治疗组复发率为43.37%,对照组复发率为71.20%,两者之间差异有统计学意义(P〈0.01)。结论:咪唑斯汀联合口服白芍总苷胶囊可能对慢性特发性荨麻疹治疗、预防复发有一定的作用。

关 键 词:咪唑斯汀  白芍总苷胶囊  慢性特发性荨麻疹  治疗

Observation of therapeutic effect of mizolastine and total glucosides of paeony capsule on chronic idiopathic urticaria
WANG Jun,MA Xiao-ling,LIU Wei-bei,CI Chao,CHANG Xiao-li,JI Bi-hua.Observation of therapeutic effect of mizolastine and total glucosides of paeony capsule on chronic idiopathic urticaria[J].Chinese Journal of Clinical Pharmacology and Therapeutics,2010,15(1):98-101.
Authors:WANG Jun  MA Xiao-ling  LIU Wei-bei  CI Chao  CHANG Xiao-li  JI Bi-hua
Institution:(Department of Dermatology, Yijishan Hospital of Wannan Medical College ,WuHu 241001 ,Anhui, China)
Abstract:AIM:To observe the therapeutic effect of mizolastine combined with total glucosides of paeony(TGP)capsule on chronic idiopathic urticaria.METHODS:According to treatment sequence,120 cases of chronic idiopathic urticaria patients were divided into two groups,the treatment group were given mizolastine and TGP,the control group only given mizolastine.RESULTS:The effective rates of the treatment group and the control group were 88%and 87%,respectively.There was no significant difference between the two groups;After 3 months,the relapse rates of the treatment group and the control group were 43.27%and 71.20%,respectively.There was significant difference between the two groups(P<0.01).CONCLUSION:Mizolastine combined with TGP capsule may be effective for the treatment and preventing the relapse of chronic idiopathic urticaria.
Keywords:Mizolastine  Total glucosides of paeony capsule  Chronic idiopathic urticaria  Treatment
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