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| 肺炎支原体感染时嗜酸细胞计数及总IgE水平变化 | |
| 引用本文： | 尹洪云,曹兰芳,陆伟蓉,朱丽君.肺炎支原体感染时嗜酸细胞计数及总IgE水平变化[J].中国医师杂志,2002(Z1):11-13. |
| 作者姓名： | 尹洪云 曹兰芳 陆伟蓉 朱丽君 |
| 作者单位： | 1. 江苏省徐州市儿童医院工作,221006 2. 上海第二医科大学附属仁济医院儿科,上海,200001 3. 上海第二医科大学附属仁济医院分子生物学试验室 |
| 摘 要： | 目的探讨肺炎支原体感染时外周血嗜酸细胞计数变化及血清总IgE水平,以阐明肺炎支原体感染与支气管哮喘发病的关系.方法对临床病人采用回顾性分析,肺炎支原体感染患儿20例(包括肺炎及支气管炎);支气管哮喘患儿30例;正常对照组25例.抗凝静脉血、伊红染色、光学显微镜下计数;ELISA方法检测血清总IgE.结果肺炎支原体感染组外周血嗜酸细胞计数和血清总IgE水平均高于正常对照组(P＜0.05),而低于支气管哮喘组(P＜0.01).结论肺炎支原体感染引起的外周血嗜酸细胞计数及血清总IgE水平增高,在持续性咳嗽和支气管哮喘发病中起着重要作用. |
| 关 键 词： | 肺炎支原体 支气管哮喘 嗜酸细胞计数 血清总IgE |
| 修稿时间： | 2001年8月1日 |
Changes of Eosinophils Count an Total IgE Levels in Patients With Myocoplasm Pneumoniae |
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| Abstract: | Objective To investigate the number of eosinophils in peripheral blood and total serum immunoglobulin E levels from children during infection of mycoplasma pneumoniae,which may elucidate what mycoplasma pneumoniae plays a role in persistent cough and asthma onset.Methods The number of eosinophils in peripheral blood was counted under microscope and total serum immunoglobulin E levels were determined by ELISA in 20 children with mycoplasmal infection ,30 patients with asthma and 25 control subjects.Results The number of eosinophils and total serum immunoglobulin E levels during mycoplasmal infection were significantly higher than in control group,and lower than in asthma.Conclusion The high eosinophil counts and total serum immunoglobulin E induced by mycoplasma pnemoniae play a key role in persistent cough and asthma attack. |
| Keywords: | Mycoplasma pneumoniae Asthma Eosinophil count Total serum immunoglobulin E |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |