依那普利联合倍他乐克治疗慢性心力衰竭临床疗效观察

目的观察依那普利、倍他乐克联合治疗慢性心力衰竭(CHF)临床疗效。方法慢性心力衰竭患者随机分为治疗组与对照组,对照组应用倍他乐克,治疗组依那普利、倍他乐克联合应用。治疗前后3个月采用NYHA分级,彩色多普勒超声心动图测量左心室收缩末期容积(LVESV)、射血分数(LVEF)、舒张晚期与早期流速峰值之比比值A/E等,对比治疗前后心功能改善情况。结果两组皆有效,治疗组左室收缩末期容积(LVESV)显著下降,左室射血分数(LVEF)显著增加,与对照组比较有显著差异性(P<0.05)。结论倍他乐克、依那普利联合组治疗慢性心力衰竭(CHF)能有效的改善心力衰竭,提高生活质量。

The Clinical Observation of Enalapril Metoprolol in the Treatment of CHF

Objective Observed with enalapril,metoprolol in the treatment of CHF therapy.Methods Chronic heart failure were randomly divided into treatment group and control group,control group received metoprolol,treatment group combined recieve enalapril and metoprolol.Before and after treatment for three months by NYHA classification,color Doppler echocardiography LVESV,LVEF,peak late diastolic velocity ratio and early ratio A/E,etc,compared to treatment improvement of cardiac function before and after.Results Groups are both effective,in the treatment group LVESV were significantly decreased,LVEF increased significantly compared with the control group was significantly different（P〈0.05）.Conclusion Metoprolol with enalapril treat of CHF can improve heart failure,improve quality of life.