| 正交试验研究功血宁颗粒的提取工艺 |
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| 引用本文： | 黄顺旺,陈师农.正交试验研究功血宁颗粒的提取工艺[J].安徽医药,2011,15(8):949-950. |
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| 作者姓名： | 黄顺旺 陈师农 |
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| 作者单位： | 安徽中医学院,安徽,合肥,230038;安徽省药物研究所·安徽省中药研究与开发重点实验室,安徽,合肥,230022;安徽省药物研究所·安徽省中药研究与开发重点实验室,安徽,合肥,230022 |
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| 摘 要： | 目的优选功血宁颗粒的最佳提取工艺。方法采用正交试验设计,以黄芪甲苷为指标,选择加水量、煎煮时间、煎煮次数三个因素,考察对提取效果的影响。结果最佳工艺组合确定为A3B2C2,即黄芪等八味药材加水煎煮2次,每次加入8倍量水,煎煮2 h。结论优选出的提取工艺为功血宁颗粒的制备提供了依据。
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| 关 键 词： | 功血宁颗粒 黄芪甲苷 正交试验 |
Study on process for extraction of gongxuening granules by orthogonal test |
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| HUANG Shun-wang,CHEN Shi-nong.Study on process for extraction of gongxuening granules by orthogonal test[J].Anhui Medical and Pharmaceutical Journal,2011,15(8):949-950. |
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| Authors: | HUANG Shun-wang CHEN Shi-nong |
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| Institution: | HUANG Shun-wang1,2,CHEN Shi-nong2 (1.Anhui College of TCM,Hefei 230038,China,2.Anhui Provincial Institute of Pharmacology,Key Laboratory of Research and Development of TCM,Hefei 230022,China) |
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| Abstract: | Aim To optimize the extracting techniques of Gongxuening granules.Methods The extraction technique was selected by orthogonal method,with the contents of Astragaloside Ⅳ as index,the influential factors for the extraction of effective ingredients that included the amount of adding water,length of decocting time and frequencies of decocting were studied.Results The optimal extraction is as follows：adding 8 times amount of water and boiling for 120 min each time,extracting two times in all.Conclusion The optimal extraction technique was stable and feasible. |
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| Keywords: | gongxuening granules astragaloside Ⅳ orthogonal Test |
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