| 胶质细胞源性神经生长因子与慢传输性便秘 |
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| 引用本文： | 李延玲,范一宏. 胶质细胞源性神经生长因子与慢传输性便秘[J]. 国际消化病杂志, 2008, 28(6) |
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| 作者姓名： | 李延玲 范一宏 |
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| 作者单位： | 浙江中医药大学第一附属医院消化内科,310006 |
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| 摘 要： | 慢传输型便秘(STC)至今病因未明。肠神经系统(ENS)可独立调节肠道功能,其在慢传输型便秘中的改变具有重要意义。胶质细胞源性神经营养因子(GDNF)不仅可促进多种神经元的存活与分化,而且对多种原因造成的神经损伤具有明显的保护作用。此文主要从肠神经系统的功能变化和胶质细胞源性神经营养因子的营养作用这两方面来阐述与功能性便秘之间的相关性。
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| 关 键 词： | 慢传输型便秘 肠神经系统 胶质细胞源性神经生长因子 |
Glial cell line-derived neurotrophic factor and slow transit constipation |
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| LI Yan-ling,FAN Yi-hong. Glial cell line-derived neurotrophic factor and slow transit constipation[J]. International Journal of Digestive Disease, 2008, 28(6) |
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| Authors: | LI Yan-ling FAN Yi-hong |
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| Abstract: | Slow transit constipation's(STC)etiopathogenisis is not clearly.Enteric nervous system(ENS)is able to independently regulate bowel function and its changes in the slow transit constipation is of great significance.Glial cell line-derived neurotrophic factor not only promotes the survival and differentiation of various neural neurons,but also protects neural injuries caused by a variety of reasons.This review will elaborate the relationship between psychological state and level of activity of enteric nerve system in patients with slow transit constipation. |
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| Keywords: | Slow transit constipation Enteric nervous system Glial cell line-derived neurotrophic factor |
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