The early risk of multiple sclerosis after optic neuritis. |
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| Authors: | D H Miller I E Ormerod W I McDonald D G MacManus B E Kendall D P Kingsley I F Moseley |
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| Affiliation: | Institute of Neurology, London, UK. |
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| Abstract: | Serial brain MRI was performed in 53 patients with clinically isolated optic neuritis. Using clinical and imaging evidence for relapse, multiple sclerosis developed within a mean of 12 months in 19 of 34 cases (56%) with brain lesions at presentation, and in only 3 of 19 cases (16%) without (Relative Risk = 6.8, p less than 0.005). |
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