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Transformation of polycythemia vera to myelofibrosis and late appearance of a 5q— Chromosome anomaly |
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| Authors: | Herman Van Den Berghe Angeline Broeckaert-van Orshoven Andries Louwagie Robrecht Verwilghen Jean-Louis Michaux Gerard Sokal |
| Affiliation: | 1. Division of Human Genetics, Department of Human Biology, University of Leuven, Leuven, Belgium.;2. Division of Hematology, Department of Medical Research, University of Leuven, Leuven, Belgium.;3. Division of Hematology, Department of Internal Medicine, University of Louvain-in-Brussels, Belgium. |
| Abstract: | A characteristic 5 q− interstitial deletion was found to occur late during the course of the disease in three patients with polycythemia vera, and accompanied the transformation to myelofibrosis and the appearance of a preleukemic disorder. |
| Keywords: | Address requests for reprints to: Dr. Herman Van Den Berghe Academisch Ziekenhius Sint-Rafaël 3000 Leuven Kapucijnenvoer 33 Leuven Belgium. |
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