| 壬基酚对雄性动物生殖系统的影响 |
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| 引用本文： | 康丽娜,王勇,韩晓冬. 壬基酚对雄性动物生殖系统的影响[J]. 中华男科学杂志, 2003, 9(7): 539-542 |
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| 作者姓名： | 康丽娜 王勇 韩晓冬 |
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| 作者单位： | 南京大学医学院免疫与生殖生物学实验室,江苏,南京,210093 |
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| 基金项目： | 南京大学“985”工程基金，“高等学校骨干教师资助计划”项目资助 |
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| 摘 要： | 壬基酚 (NP)是一种环境内分泌干扰物 (EDs) ,而EDs已成为当前环境医学领域的研究重点之一。壬基酚聚氧乙烯醚 (NPEs)作为非离子表面活性剂被广泛用于工业生产及家庭洗涤。NPEs经生物降解转化为NP ,后者可能通过雌激素效应或毒性作用对雄性动物的生殖系统产生有害影响。本文就当前NP的研究进展及本实验室的研究动态进行总结 ,评估NPEs类物质对雄性动物生殖系统的危害 ,为限制这类化合物的使用提供依据
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| 关 键 词： | 壬基酚 环境内分泌干扰物 壬基酚聚氧乙烯醚 生殖系统 |
| 文章编号： | 1009-3591(2003)07-0539-04 |
| 修稿时间： | 2003-04-28 |
Effects of Nonylphenol on the Reproductive System of Male Animals |
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| Li Na KANG,Yong WANG,Xiao Dong HAN. Effects of Nonylphenol on the Reproductive System of Male Animals[J]. National journal of andrology, 2003, 9(7): 539-542 |
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| Authors: | Li Na KANG Yong WANG Xiao Dong HAN |
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| Affiliation: | Laboratory of Immunology and Reproductive Biology, Medical College, Nanjing University, Nanjing, Jiangsu 210093, China. |
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| Abstract: | The research on endocrine disrupters has become one of the key directions in the field of environmental medical science. Nonylphenol ethoxylates (NPEs) are widely used in industry and family washing as one of the non ionic surfactants. NPEs can be degraded biologically to nonylphenol (NP), whose estrogenic effects or toxicity may do harm to the reproductive systems of male fish, amphibians and mammals. Thus it is an urgent affair to develop perfect assays, evaluate the harm of these chemicals to human beings, find the exact mechanism of action and restrict the use of NPEs. |
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| Keywords: | Nonylphenol Endocrine disrupters Nonylphenol ethoxylates Reproductive system |
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