Clinical Significance of Incidental Colonic 18F-FDG Uptake on PET/CT Images in Patients with Gastric Adenocarcinoma |
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| Authors: | Jung Ho Shim Joo Hyun O Seong Il Oh Han Mo Yoo Hae Myung Jeon Cho Hyun Park Sung Hoon Kim Kyo Young Song |
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| Affiliation: | 1. Division of Gastrointestinal Surgery, Department of Surgery, Seoul St. Mary??s Hospital, College of Medicine, The Catholic University of Korea, 505 Banpo-dong, Seocho-gu, Seoul, 137-701, South Korea
2. Department of Radiology, The Catholic University of Korea, Seoul, South Korea
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| Abstract: | Background and Objectives We assessed the ability of positron emission tomography?Ccomputed tomography (PET/CT) to detect synchronous colonic pathology and determined the significance of 18F-fluorodeoxyglucose (18F-FDG) activity in the colon of gastric cancer patients. Methods A total of 239 gastric cancer patients who underwent PET/CT and colonoscopy preoperatively were included. FDG uptake patterns on PET/CT were classified as (1) group A, focal; (2) group B, diffuse; and (3) group C, no uptake. The PET/CT findings were compared with the results of concurrent colonoscopy. Results In group A, a total of 123 polyps of >0?mm were observed. Of these, nine polyps were colonic adenocarcinomas and six were high-grade dysplasia. The incidence of colonic adenocarcinomas was significantly higher in group A than in the other two groups (p?=?0.037). There was a significant correlation between SUVmax values and incidence of colonic polyps of >10?mm (r?=?0.471, p?=?0.04). The distribution pattern of SUVmax in polyps with adenoma (>10?mm) was less homogenous than in polyps (>10?mm) with adenocarcinoma. Conclusions The focal colonic FDG uptake in PET/CT requires colonoscopic confirmation. The suspicion of colonic malignancy increased in the presence of polyps >10?mm that showed a positive correlation with the SUVmax. |
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