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Symptomatic splenic hamartoma with renal, cutaneous, and hematological abnormalities
Authors:A. Kassarjian  Y. G. Patenaude  C. Bernard  L. Bell
Affiliation:(1) Department of Medical Imaging, The Montreal Children's Hospital, 2300 Tupper Street, Montreal, Quebec, Canada, H3H 1P3 Tel.: + 1-5 14-9 34 44 50 Fax: + 1-5 14-9 34 43 47 e-mail: yves.patnaude@muhc.mcgill.ca, CA;(2) Department of Pathology, The Montreal Children's Hospital, 2300 Tupper Street, Montreal, Quebec, Canada, H3H 1P3, CA;(3) Department of Nephrology, The Montreal Children's Hospital, 2300 Tupper Street, Montreal, Quebec, Canada, H3H 1P3, CA
Abstract:Background. There is a rare association between splenic hamartomas and hematological abnormalities with, to our knowledge, only 24 reported cases in the English literature.¶Patients and methods. We report a case of a splenic hamartoma in a 14-year-old boy associated with membranoproliferative glomerulonephritis, multiple lobular capillary hemangiomas of the skin, hypertension, and anemia. Following imaging with ultrasonography, MRI, and nuclear scans, a hamartoma was suspected, but malignancy could not be excluded. The lesion was removed by partial splenectomy, and pathological examination confirmed the presence of a red pulp splenic hamartoma.¶Results. The renal, hematological, and dermatological abnormalities resolved following removal of the splenic hamartoma. This is the first reported case of a splenic hamartoma associated with renal, cutaneous, and hematological abnormalities and only the second reported case of a symptomatic splenic hamartoma treated by partial splenectomy.
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