| 顺式阿曲库铵应用于肾功能不全患者麻醉的临床研究进展 |
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| 引用本文： | 许敏,魏昕,方才. 顺式阿曲库铵应用于肾功能不全患者麻醉的临床研究进展[J]. 麻醉与监护论坛, 2011, 0(6): 443-445 |
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| 作者姓名： | 许敏 魏昕 方才 |
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| 作者单位： | 安徽医科大学附属省立医院麻醉科,合肥230001 |
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| 摘 要： | 本文综述了顺式阿曲库铵的理化特性、代谢途径及其应用于肾功能不全患者的药效学观察等研究的现状和进展。顺式阿曲库铵作为一种新型的中时效非去极化肌松药．不释放组胺．不依赖肝肾代谢．且无蓄积作用．恢复较快．安全治疗窗宽．是目前较为理想的可以用于肾功能不全患者的麻醉肌松药。
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| 关 键 词： | 顺式阿曲库铵 肌肉松弛剂 肾功能不全 全身麻醉 |
Clinical Study of Cisatracurium in Patients Undergoing Renal Dysfunction |
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| Min Xu Xin Wei Cai Fang. Clinical Study of Cisatracurium in Patients Undergoing Renal Dysfunction[J]. , 2011, 0(6): 443-445 |
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| Authors: | Min Xu Xin Wei Cai Fang |
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| Affiliation: | Min Xu Xin Wei Cai Fang Department of Anesthesiology on Anhui Provincial Hospital Affiliated to Anhui Medical University,Hefei 230001,Ghina |
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| Abstract: | The overview aimed at evaluating cisatracurium which is an ideal non-depolarizing neuromuscular blocking agent （NABA） from its physical and chemical properties, metabolic pathway, and efficacy observation for patient with renal dysfunction. Cisatracurium seems to be beneficial, especially for patients with renal dysfunction, due to organ-independent Hofmann elimination and a lower trend to histamine release. |
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| Keywords: | cis-atracurium muscle relaxant renal dysfunction general anaesthesia |
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