704例不孕不育患者性病病原体感染回顾性分析

目的:了解不孕不育患者常见性病病原体的分布情况.方法:采用随机抽取的方法,选取2009年1月至2011年12月间704例不孕不育患者,进行分泌物和外周血检测,分别采用培养法、涂片法、ELISA、TRUST、HIV抗体法检测解脲支原体(Uu)和淋球菌、念珠菌、衣原体、梅毒和艾滋病病毒.结果:有220例阳性患者,总感染率为31.25%.Uu阳性率为209/704(29.68%),其中女性Uu阳性率为204/603(33.83%),男性Uu阳性率为5/101(4.95%),男、女比较有统计学差异;其次为念珠菌37/704(5.26%)、衣原体8/704(1.14%),梅毒6/704(0.86%);淋病1/704(0.14%);HIV未检出.结论:泌尿生殖道的性病病原体感染可能是不孕不育原因之一,性病可危害下一代健康,有必要进行相关病原体检测,尽早诊断和治疗.

Retrospective Analysis on Sexually Transmitted Infection of 704 Cases with Infertility

Objective：To evaluate the STDs related microorganisms on the patients with infertility. Methods ：704 patients with infertility were enrolled randomly in the study, and the pathogens ineluding Uu and Neisseria gonorrhoeae, Candida, Chlamydia trachomatis, syphilis, HIV were detected by culture, smear, ELISA, TRUST and HIV antibody, respectively. Results： STDs were detected on 220 patients with total infection rate of 31.25%. Positive rate for Uu was 29. 68% （209/ 704）, and it was 33.83% for females （204/603） and 4. 95% for males （5/101）. Positive rate for Candida, Chlamydia, syphilis, Neisseria gonorrhoeae was 5.26% （ 37/704）, 1.14% （ 8/704 ）, 0.86% （6/704） and 0. 14% （1/704） , respectively. None case showed HIV positive. Conclusion ： Genitourinary tract infected by STDs pathogens may be the one of reasons in those cases with infertility. It is necessary to detect the relevant pathogens for early diagnosis and treatment.