Serotonin Metabolism Parameters in Patients with Chronic Hepatitis and Liver Cirrhosis |
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| Authors: | A S Alekseeva E I Beloborodova M I Rachkovskiy E L Naumova E G Lambrov L P Philippova |
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| Institution: | (1) Department of Therapy, Faculty of Upgrading and Postgraduate Training of Physicians, Siberian State Medical University, Tomsk, Russia |
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| Abstract: | We studied disorders in serotonin metabolism in patients with chronic hepatitis and cirrhosis of the liver with and without
inflammatory process (cytolysis syndrome) and their impact for the formation of depressive disorders. Blood serotonin content
decreased in patients with cirrhosis of the liver with pronounced depressive disorders. Serum serotonin level was elevated
in all patients with the cytolysis syndrome.
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 146, No. 11, pp. 512–514, November, 2008 |
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| Keywords: | chronic hepatitis liver cirrhosis serotonin depressive disorders cytolysis syndrome |
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