烧伤休克期复苏补液的计算机仿真设计及应用研究

目的 :为建立一种新的科学的烧伤休克期复苏补液方法 ,使烧伤病人平稳渡过休克期 ,并使水肿较轻。方法 :根据烧伤病人休克期液体和蛋白质平衡的数学模型 ,利用系统控制的计算机仿真技术 ,对 36例病人进行液体复苏治疗 (实验组 ) ,并与采用经验公式复苏的 32例病人进行比较 (对照组 )。结果 :实验组较对照组病人更加平稳渡过休克期 ,而水肿 (净体重增加 )较轻 ,且平均住院时间、医疗费用及并发症也少 (P <0 0 5 )。结论 :计算机仿真设计的烧伤休克期液体复苏方案比经验公式科学、合理 ,既能使烧伤病人平稳渡过休克期 ,又可减轻水肿 ,且具有个体化的特点

Computer simulation design of fluid resuscitation at the shock stage of burn and its application

Objective: To establish a new scientific method for fluid resuscitation to help patients tie over the shock stage smoothly and lessen the edema. Method: According to the mathematical model of the body fluid and protein balance of burn patient at shock stage, using the technique of computer simulation under a system control, 36 burn patients were treated with fluid resuscitation (experimental group) and the results were compared with that of 32 patients treated according to empirical formula (control group). Result: Patients in experimental group tied over the shock stage more smoothly than those in control group and had lessened edema. The average time of hospital stay was shortened and the cost reduced. The incidence of complications was reduced (P<0.05). Conclusion: Computer simulation design of fluid resuscitation is more scientific and rational. It can help the patients tie over the shock stage more smoothly and lessen the edema. It has the characteristic of individualization.