腭裂患者302例临床资料分析

目的通过回顾性调查，了解河南省先天性腭裂的患病情况与特点，从而规范河南省唇腭裂患者的综合序列治疗。方法收集2005年8月至2009年12月期间在郑州大学第一附属医院口腔科进行腭裂手术及腭裂术后二期修复的302例腭裂患者的临床病历资料，并将所得数据进行统计分析。结果在本纽病例中，男性患者172例，女性患者130例，年龄1．5～41岁，中位年龄3．6岁，男女比例约为1．32：1；单纯腭裂的发生男女差异无统计学意义，而唇腭裂的发生男女性别差异有统计学意义；单纯腭裂和腭裂伴有唇裂的发生率差异有统计学意义；在腭裂的构成比中，主要以不完全腭裂为主，占70．86％，完全腭裂占19．87％，腭裂术后穿孔占6．29％。结论单纯腭裂的发生男女无明显性别差异；而唇腭裂的发生男女性别差异有统计学意义，男性约是女性的3倍；单纯腭裂的发病率明显高于腭裂伴有唇裂的发病率；在腭裂的构成比中，主要以不完全腭裂为主；腭瘘仍是目前腭裂术后最常见的并发症。

Clinical analysis of 302 cases of cleft palate

Objective To investigate the characteristics and features of cleft palate and improve comprehensive and sequential therapy of cleft lip and palate （CLP） in Henan province by a retrospective study. Methods A total of 302 CLP were included in the retrospective study, who underwent primary and secondary cleft palate repair during August 2005 to December 2009. Results Three hundred and two patients （172 males,130 females,age ranged from 1.5 years to 41 years with a median age of 3.6 years） were included in the study. There was no significant gender difference in cleft palate, but in cleft lip and palate. And there was significant rate difference between cleft palate and cleft lip and palate. Ac- cording to cleft types, 214 patients （70.86%） were incomplete cleft palate, 60 patients（ 19.87% ） were complete cleft palate, 12 patients（3.97% ） were cleft soft palate, 19 patients（6.29% ） were palate fistula. Conclusions There was no significant gender differences in cleft palate, but in cleft lip and palate. The incidence of cleft palate was significantly higher than that of cleft lip and palate, and incomplete cleft palate was the main cleft palate type. Palate fistula was still the most common complication.