女性生殖道感染支原体分布及药敏结果分析

目的探讨女性生殖道支原体感染及耐药性变迁情况，为临床提供最新的流行病学资料及用药指导。方法应用板条培养药敏试剂法对解脲支原体（Uu）和人型支原体（Mh）进行检测，并对11种抗菌药物的药敏试验结果进行分析。结果2405例疑似非淋球菌性尿道炎（NGU）患者中，支原体感染总阳性例数1035例，阳性率为43．04％。其中Uu阳性836例（34．76％），Mh阳性43例（1．79％），Uu＋Mh阳性混合感染156例（6．49％）。21～40岁患者支原体培养阳性率为46．23％，明显高于其他年龄段患者（P〈0．05）。药敏结果表明，支原体对交沙霉素、美满霉素、强力霉素敏感率高（分别为99．22％，98．16％，97．68％），对环丙沙星的耐药率最高（64．06％）。结论Uu在女性NGU疑似患者中感染率较高，年龄以21～40岁多见；临床对支原体感染治疗应根据药敏结果合理使用抗生素，以减少耐药菌株产生。

Mycoplasma distribution and drug susceptibility results in female reproductive tract infection

Objective To investigate the changes of female reproductive tract mycoplasma infection and drug resistance, to provide the latest epidemiological information and direction. Methods Application of antimicrobial susceptibility reagent method wattle cultivation to test the Ureaplasma urealyticurn（Uu） and Mycoplasma hominis （Mh）, and analysed the antimicrobial susceptibility test results of 11 kinds of antibacterial drugs. Results There were 1035 cases of mycoplasma infection always positive in 2405 patients who were suspected non - gonococcal infection, positive rate was 43.04%. And Uu masculine gender was 836 cases （34.76%） ,Mh masculine gender was 43 cases （ 1.79% ） ,Uu ＋ Mh mixed infection was 156 cases （6.49%）. The positive rate of mycoplasma training between 21 to 40 years was 46.23 %, obviously higher than other ages patients （ P 〈 0.05 ）. Antimicrobial susceptibility test results show that, mycoplasma had a high sensitive in josamycin, mincycline, doxycycline （each was 99.22%, 98.16% ,97.68% ） , the most resistance was the ciprofloxacin （64.06%）. Conclusions There had a high infection rate of Uu in female NGU, especially in 21 to 40 years. Clinical could reasonable use of antibiotics according to antimicrobial susceptibility test results in treatment of mycoplasma infection, to reduce drugresistant strains.