| 黄芪注射液联合缬沙坦治疗糖尿病肾病的效果观察 |
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| 引用本文： | 张颖.黄芪注射液联合缬沙坦治疗糖尿病肾病的效果观察[J].华北国防医药,2012,24(8):52-54. |
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| 作者姓名： | 张颖 |
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| 作者单位： | 解放军254医院内分泌科,天津,300142 |
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| 摘 要： | 目的 观察黄芪注射液联合缬沙坦治疗糖尿病肾病(diabetic nephropathies,DN)的疗效.方法 60例患者随机分为治疗组和对照组各30例.两组均给予常规治疗,对照组在常规治疗的基础上口服缬沙坦,治疗组在对照组基础上静脉滴注黄芪注射液,两组疗程均为3周.结果 治疗组总有效率高于对照组,差异有统计学意义(P<0.05).两组治疗后24 h尿蛋白定量、尿微量白蛋白及血肌酐均较治疗前降低,且治疗组低于对照组,差异均有统计学意义(P<0.05).结论 黄芪注射液联合缬沙坦治疗DN,在降低24 h尿蛋白定量、尿微量白蛋白和血肌酐方面有较好疗效.
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| 关 键 词： | 糖尿病肾病 黄芪 缬沙坦 治疗结果 |
Effect of Astragalus Injection Combined with Valsartan in Treating Diabetic Nephropathy |
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| ZHANG Ying.Effect of Astragalus Injection Combined with Valsartan in Treating Diabetic Nephropathy[J].Medical Journal of Beijing Military Region,2012,24(8):52-54. |
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| Authors: | ZHANG Ying |
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| Institution: | ZHANG Ying(Department of Endocrinology,the 254th Hospital of PLA,Tianjin 300142,China) |
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| Abstract: | Objective To observe the effect of astragalus injection combined with valsartan in treating diabetic nephropathy（DN）.Methods 60 patients with diabetic nephropathy were randomly divided into two groups（n=30）,which were both given conventional therapy.The control group took orally valsartan daily while the therapy group were treated with astragalus injection and valsartan daily both for three weeks.Results The total effective rate of therapy group was statistically higher than that of control group（P0.05）.The proteinuria,trace of uro-albumin and the serum creatinine after treatment were all decreased obviously compared with the index before treatment（P0.05）.Conclusion Astragalus injection combined with valsartan in treating patients with diabetic nephropathy can decrease the level of urine protein,trace of albumin and the serum creatinine. |
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| Keywords: | Diabetic nephropathies Astragalus membranaceus Valsartan Treatment outcome |
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