Prediction Model for Low Birth Weight and its Validation |
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| Authors: | Avantika Singh Sugandha Arya Harish Chellani K. C. Aggarwal R. M. Pandey |
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| Affiliation: | 1. Division of Neonatology, Department of Pediatrics, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, 110029, India
2. Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India
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| Abstract: | Objective To evaluate the factors associated with low birth weight (LBW) and to formulate a scale to predict the probability of having a LBW infant. Methods This hospital based case–control study was conducted in a tertiary care university hospital in North India. The study included 250 LBW neonates and 250 neonates with birth weight ≥2,500 g. Data were collected by interviewing mothers using pre-designed structured questionnaire and from hospital records. Results Factors significantly associated with LBW were inadequate weight gain by the mother during pregnancy (<8.9 kg), inadequate proteins in diet (<47 g/d), previous preterm baby, previous LBW baby, anemic mother and passive smoking. The prediction model made on these six variables has a sensitivity of 71.6 %, specificity 67.0 %, positive LR 2.17 and negative LR of 0.42 for a cut-off score of ≥29.25. On validation, it has a sensitivity of 72 % and specificity of 64 %. Conclusions It is possible to predict LBW using a prediction model based on significant risk factors associated with LBW. |
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