| Hepatitis B virus S gene enhances immune responses of a multiple-epitope DNA construct of hepatitis C virus in mice |
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| 引用本文： | YU PING GONG,JUN GAO,PING ZHAO,XIAO PING YANG and ZHONG TIAN QI Department of Microbiology,Key Laboratory for Medical Microbiology of PLA,Second Military Medical University,Shanghai,P.R.China. Hepatitis B virus S gene enhances immune responses of a multiple-epitope DNA construct of hepatitis C virus in mice[J]. 中华微生物学和免疫学杂志(英文版), 2005, 3(1): 40-46 |
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| 作者姓名： | YU PING GONG JUN GAO PING ZHAO XIAO PING YANG and ZHONG TIAN QI Department of Microbiology Key Laboratory for Medical Microbiology of PLA Second Military Medical University Shanghai P.R.China |
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| 作者单位： | YU PING GONG，JUN GAO，PING ZHAO，XIAO PING YANG and ZHONG TIAN QI Department of Microbiology，Key Laboratory for Medical Microbiology of PLA，Second Military Medical University，Shanghai，P.R.China |
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| 摘 要： | Hepatitis C virus (HCV) is a major causative agent of acute and chronic hepatitis and mainlytransmitted by blood routes. It is estimated thatthere are 170 million HCV infected individualsworldwide, and so far, interferon γ(IFN γ) com bined with ribavirin treatment is a commonly ac cepted therapeutic strategy. However, only about40% of treated patients develop long term respons es[1]. The hypervariable region 1(HVR1) of theHCV E2 envelope protein is critically …
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| 关 键 词： | 乙型肝炎病毒 丙型肝炎病毒 免疫反应 DNA 抗原决定基 |
Hepatitis B virus S gene enhances immune responses of a multiple-epitope DNA construct of hepatitis C virus in mice |
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| YUPINGGONG JUNGAO PINGZHAO XIAOPINGYANG ZHONGTIANQI. Hepatitis B virus S gene enhances immune responses of a multiple-epitope DNA construct of hepatitis C virus in mice[J]. Chinese Journal of Microbiology and Immunology, 2005, 3(1): 40-46 |
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| Authors: | YUPINGGONG JUNGAO PINGZHAO XIAOPINGYANG ZHONGTIANQI |
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| Affiliation: | DepartmentofMicrobiology,KeyLaboratoryforMedicalMicrobiologyofPLA,SecondMilitaryMedicalUniversity,Shanghai,P.R.China |
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| Abstract: | |
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| Keywords: | Hepatitis C virus Vaccine DNA construct Hepatitis B surface antigen Multiple-epitope Immune responses |
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