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大剂量盐酸氨溴索治疗早产儿呼吸窘迫综合征疗效观察
引用本文:合力.大剂量盐酸氨溴索治疗早产儿呼吸窘迫综合征疗效观察[J].昆明医学院学报,2011,32(2):121-123.
作者姓名:合力
作者单位:西双版纳州人民医院儿科,云南,景洪,666100
摘    要:目的探讨盐酸氨溴索对治疗早产儿呼吸窘迫综合征的疗效.方法将72例NRDS早产儿随机分成治疗组37例和对照组35例.两组均给予相同综合基础治疗及鼻塞式cpap给氧,治疗组加用盐酸氨溴索注射液30mg/(kg.d)分4次静脉给药,比较两组在治疗后48h的临床表现及血气变化,(PaO2、PaCO2及Pa02/FiO2).结果治疗组21例经治疗48h后,呼吸困难和呻吟明显减轻或消失,血PaO:升高,PaCO:降低,氧和参数明显增加.两组疗效及血气,氧和指数比较有显著性差异.结论在早产儿呼吸窘迫综合征常规治疗的基础上加用大剂量盐酸氨溴索有较好疗效,可以减少病死率,提高存活率.

关 键 词:盐酸氨溴索  呼吸窘迫综合征  新生儿  早产儿

Therapeutic Effect of Large Dose of Mucosolvan on Respiratory Distress Syndrome in Premature Children
HE Li.Therapeutic Effect of Large Dose of Mucosolvan on Respiratory Distress Syndrome in Premature Children[J].Journal of Kunming Medical College,2011,32(2):121-123.
Authors:HE Li
Institution:HE Li(Dept.of Pediatrics,The People's Hospital of Xishuangbanna State,Jinhong Yunnan 666100,China)
Abstract:Objective To investigate the therapeutic effect of large dose of mucosolvan on respiratory distress syndrome in premature children.Methods Seventy-two premature children with NRDS were randomly divided into treatment group(37 cases)and control group(35 cases),all cases were given same combined therapy and variant flow rate continuous positive airway by nasal mask.The cases in treatment group were given 30 mg/(kg.d)of mucosolvan for four times.The clinical symptoms and blood gas analysis(PaO2,PaCO2,PaO2/FiO2...
Keywords:Ambroxol hydrochloride  Respiratory distress syndrome  Neonatal  Premature children  
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