Reduced neural responses to food cues might contribute to the anorexigenic effect of acute exercise observed in obese but not lean adolescents |
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| Affiliation: | 1. Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA, USA;2. Brain and Metabolism Imaging in Chonic Disease, LSU Pennington Biomedical Research Center, Baton Rouge, LA, USA;3. Clermont Université, Université Blaise Pascal, Laboratoire de Psychologie Sociale et Cognitive, BP 10448, F-63000 Clermont-Ferrand, France;4. CNRS, UMR 6024, LAPSCO, F-63037 Clermont-Ferrand, France;5. Clermont-Ferrand University hospital, Biostatistics unit (DRCI), Clermont-Ferrand, France;6. Department of Human Nutrition, Clermont-Ferrand University Hospital, G. Montpied Hospital, Clermont-Ferrand, France;7. University Clermont 1, UFR Medicine, Clermont-Ferrand, France;8. INRA, UMR 1019, Clermont-Ferrand, France;9. CRNH-Auvergne, Clermont-Ferrand, France;10. Department of Sport Medicine and Functional Explorations, Clermont-Ferrand University Hospital, G. Montpied Hospital, Clermont-Ferrand, France;11. Department of Food Science, The Pennsylvania State University, University Park, PA, USA;12. Clermont Auvergne University, EA 3533, Laboratory of the Metabolic Adaptations to Exercise under Physiological and Pathological Conditions (AME2P), Clermont-Ferrand, France;3. Department of Kinesiology, The University of Alabama, Tuscaloosa, AL, 35487, USA;4. Department of Pediatrics, University of Alberta, 11405-87 Avenue, Edmonton, AB, T6G 2R3, Canada;1. Department of Psychology, University of Tuebingen, Schleichstraße 4, 72070 Tübingen, Germany;2. Department of Psychology, University of Freiburg, Engelbergerstraße 41, 79085 Freiburg;3. Clinic of Tumorbiology, Breisacherstraße 17, 79106 Freiburg;4. Department of Psychiatry, University Hospital of Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain;1. Institute of Human Nutrition, Columbia University College of Physicians and Surgeons, New York, NY, USA;2. Department of Medicine, New York Obesity Nutrition Research Center, Mount Sinai St. Luke''s-Roosevelt Hospital, New York NY, USA;3. Department of Physiology and Cellular Biophysics, Columbia University Medical Center, New York, NY, USA;4. fMRI Research Lab, Columbia University Medical Center, New York, NY, USA;5. Department of Psychology, Touro College, New York, NY, USA;6. Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA;7. Department of Medicine -Endocrinology, Columbia University Medical Center, New York, NY, USA |
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| Abstract: | Acute exercise has been found to reduce subsequent energy intake in obese adolescents. Although it has been suggested that some neural pathways are involved in this post-exercise energy intake regulation, it remains unknown whether the post-exercise attentional response to food cues differs as a function of weight status. We hypothesize that there will be a reduction in the neural response to food cues as a result of exercise in obese adolescents, but not in their lean counterparts. Fourteen obese and 14 lean adolescent boys (12-15 years) were randomized (within-subjects design) to remain seated (CON) or to exercise 45 minutes at 65% of their maximal capacities (EX). After the exercise or sitting period, the adolescents' cognitive engagement in the processing of food vs. non-food cues was assessed during an attentional computer-based task with electroencephalography (EEG) recording. An ad libitum lunch meal was offered and appetite feelings were assessed (visual analog scales). There was no main effect of condition on energy intake in lean subjects, but obese adolescents ate significantly less following EX compared with CON (P < .05). There was no effect of condition or stimulus type (food vs. non-food) on the EEG-recorded amplitude of the P3b component in lean adolescents. However, the response to food cues was significantly reduced compared with non-food stimuli after exercise in obese participants (P < .01). Following EX, but not CON, total body weight, body mass index, and fat mass were inversely correlated with the EEG response to food–non-food stimuli (all P < .05). However, this response was not associated with ad libitum EI (both P > .1). Acute exercise favors decreased neural response to food cues compared with non-food cues in obese but not lean adolescents, suggesting differential effects of exercise on the neural processing of food cues based on weight status. |
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