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Retrospective clinical and laboratory evaluation of children with brucellosis
Authors:Mesut Okur  Fatih Erbey  Mehmet Selçuk Bektaş  Avni kaya  Murat Doğan  Mehmet Nuri Acar  Hakan Uzun
Institution:1. Department of Pediatrics, Düzce University Medical Faculty, Düzce;2. Department of Pediatric Oncology, Women's and Children's Hospital;3. Department of Pediatrics, Yüzüncü Y?l University Medical Faculty, Van, Turkey
Abstract:Background: Acute brucellosis is a zoonotic disease seen in childhood, with non‐specific complaints and clinical findings that can affect the locomotor, gastrointestinal, genitourinary, hematologic, cardiovascular, respiratory, and central nervous systems. Particularly in endemic regions, it occurs as a result of consumption of unpasteurized milk and dairy products. In this study, clinical and laboratory findings of children with acute brucellosis are presented. Methods: Data for 147 patients, aged 2–16 years, were evaluated retrospectively. Results: The most frequent complaints and clinical findings were abdominal pain and fever. Other complaints and clinical findings included arthralgia, myalgia, loss of appetite, weakness, sweating, fatigue, headache, arthritis, hepatomegaly, and splenomegaly. Anemia was the most frequent hematological abnormality detected; other abnormalities included leukopenia, thrombocytopenia, and pancytopenia. Conclusion: Childhood brucellosis can cause non‐specific complaints and particularly anemia and leukopenia as hematological abnormalities. It is easily treated, however, with appropriate antibiotics.
Keywords:brucellosis  childhood  clinical and laboratory findings
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