屏气采集配合ultraHD重建技术改善PET/CT检查肺部代谢灶融合不良

目的比较吸气后屏气采集配合ultra HD重建法较传统自由呼吸法在改善肺部病灶PET/CT检查受呼吸运动而导致融合不良的作用大小。方法制定入组条件:患者常规PET/CT检查CT图像可见明确占位性病灶,PET有明确与之对应的高代谢灶,患者有相应的CT需屏气采集检查史且屏气效果良好,可以对技师的屏气指令做出良好配合。按上述入组条件依次抽取2019年1~6月在某三甲医院PET/CT中心检查的患者60例,将患者常规采集所得图像作为对照组;常规检查结束后立即行肺部高代谢灶单床位吸气后屏气采集配合ultra HD重建,将所得图像作为观察组。比较对照组与观察组图像的融合质量、平均标准率摄取值（SUV_avg）、40%的肿瘤代谢体积（MTV_40%）,病灶与肝血池SUV_max的靶本比（T/B_max）,并从成像原理的基础上加以解释分析。结果对照组融合良好17例占28.33%,观察组融合良好58例占96.67%;SUV_avg观察组为8.28±2.45、对照组为6.84±2.58,观察组明显高于对照组（χ2=10.50,P<0.05）;MTV_40%观察组为5.61±4.40、对照组为7.70±5.39,观察组明显低于对照组（χ2=5.37,P<0.05）,T/B_max观察组为6.29±2.39、对照组为4.87±1.78,观察组明显高于对照组（χ2=13.71,P<0.05）。结论屏气采集配合ultra HD重建法得到的图像较传统法所得图像,融合良好占比更高;SUV_avg、MTV_40%,T/B_max测量值受部分容积效应和移动边界扩大效应的影响更小;加之更加精确的PSF在重建过程中的运用,使上述定量指标更加精确,值得肺部疾病患者临床PET/CT采集中借鉴并有针对性的酌情使用。 

Improvement of PET/CT in pulmonary metabolic lesion fusion by holding-breath scanning with ultraHD reconstruction

objective To compare the effects of breath-holding scanning with ultra HD reconstruction in improving pulmonary PET/CT detection of respiratory motion artifacts. Methods The inclusion criteria were established: clear space-occupying lesions could be seen in the CT images of the patients, the PET had a matching high uptake focus, and the patients held their breath well. According to the above inclusion conditions, 60 patients examined in PET/CT center from 2019.1-2019.6 were selected. the images obtained by routine collection were used as the control group, breath-holding scanning of single bed lung with ultra HD weighted images was used as the observation group. compared with Image fusion quality, average Standard Uptake Value, 40% of Metabolic Tumor Volume, target(high uptake foci) background(SUVMax of hepatic blood pool) ratio(T/BMax) between the control group and the observation group, try to explaination the results based on the imaging principle.Results In the control group, 17 cases had good fusion, accounting for 28.33%. In the observation group, there were 58 cases with good fusion, accounting for 96.67%. The SUVavg observation group was 8.28±2.45 and the control group was 6.84±2.58,which were significantly higher than the control group(χ^2= 10.50, P<0.05). MTV40% was 5.61±4.40 in the observation group and 7.70±5.39 in the control group, which were significantly lower than the control group(χ^2=5.37, P<0.05), 6.29±2.39 in the T/Bmax observation group and 4.87±1.78 in the control group, which were significantly higher than the control group(χ^2=13.71,P<0.05). Conclusion Hold-breath scanning with ultra HD reconstruction make imagings has a better fusion;SUVavg, MTV40%,T/B max measurements were less affected by partial volume effect and moving boundary expansion effect. In addition, the application of more accurate PSF in the reconstruction process makes the quantitative indicators more accurate, It is worthy to use PET/CT for reference in clinical PET/CT collection of patients with pulmonary diseases.