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Spread of Virulent Group A Streptococcus Type emm59 from Montana to Wyoming,USA
Authors:Christopher C. Brown  Randall J. Olsen  Nahuel Fittipaldi  Monica L. Morman  Peter L. Fort  Robert Neuwirth  Mohammed Majeed  William B. Woodward  James M. Musser
Affiliation:Campbell County Memorial Hospital, Gillette, Wyoming, USA (C.C. Brown, M.L. Morman, P. Fort, R. Neuwirth, M. Majeed, W.B. Woodward); ;Houston Methodist Research Institute, Houston, Texas, USA (R.J. Olsen, J.M. Musser); ;Houston Methodist Hospital System, Houston (R.J. Olsen, J.M. Musser); ;Public Health Ontario, Toronto, Ontario, Canada (N. Fittipaldi); ;University of Toronto, Toronto (N. Fittipaldi)
Abstract:Full-genome sequencing showed that a recently emerged and hypervirulent clone of group A Streptococcus type emm59 active in Canada and parts of the United States has now caused severe invasive infections in rural northeastern Wyoming. Phylogenetic analysis of genome data indicated that the strain was likely introduced from Montana.
Keywords:group A Streptococcus   GAS   bacteria   emm59   streptococci   invasive disease   virulence   genome sequencing   epidemiology   necrotizing fasciitis   Montana   Wyoming   United States
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