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Growth failure in vitamin D-deficient rat pups |
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| Authors: | Robert Brommage William F. Neuman |
| Affiliation: | (1) Department of Radiation Biology and Biophysics, University of Rochester Medical Center, 14642 Rochester, New York, USA;(2) Present address: Department of Biochemistry, University of Wisconsin, 53706 Madison, Wisconsin, USA |
| Abstract: | Summary Vitamin D-deficient rat pups were produced by feeding normal impregnated rats a diet deficient in vitamin D after mating. The rat pups appeared normal at birth but stopped growing at 1 week of age. Despite this growth failure, these pups were normocalcemic. Analyses of calvaria from a similar group of dams given vitamin D3 showed that these dams mobilized skeletal calcium to meet the calcium requirements of their growing pups. |
| Keywords: | Vitamin D deficiency Neonatal development Lactation Rat pups Calcium metabolism |
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