| 抗Ⅱ型胶原抗体对正常关节软骨表层组织的影响 |
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| 引用本文： | 林共周,曲绵域,林宗智,李文,刘燕,罗葶.抗Ⅱ型胶原抗体对正常关节软骨表层组织的影响[J].中国运动医学杂志,1991(4). |
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| 作者姓名： | 林共周 曲绵域 林宗智 李文 刘燕 罗葶 |
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| 作者单位： | 北京医科大学运动医学研究所
(林共周，曲绵域，林宗智，李文，刘燕)，北京医科大学运动医学研究所(罗葶) |
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| 摘 要： | 正常大鼠关节软骨表层组织在抗Ⅱ型胶原抗体的作用下,其表层胶原纤维网状结构可出现排列紊乱,失去乳头状突起等改变,但关节软骨表层结构的这种早期退行性变化在停止关节内注射抗体一段时间后可恢复正常。
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THE EFFECT OF TYPE Ⅱ COLLAGEN ANTIBODY ON THE SURFACE LAYER OF ARTICULAR CARTILAGE |
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| Lin Congzhou,et al Institute of Sports Medicine Beijing Medical University.THE EFFECT OF TYPE Ⅱ COLLAGEN ANTIBODY ON THE SURFACE LAYER OF ARTICULAR CARTILAGE[J].Chinese Journal of Sports Medicine,1991(4). |
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| Authors: | Lin Congzhou Institute of Sports Medicine Beijing Medical University |
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| Abstract: | Anti-collagen antibody was injected into the knee joint cavities of rats once per week for four times.The ultrastructural alterations in the surface layer of articular cartilage were examined by scanning electronmicroscope 1, 2, and 3 months after the first injection. It was found that the network of collagen fibers inthe surface layer became irregular and tortuous under continuous exposure to anti-collagen antibody. Howe-ver, these morphological alterations were reversible. One month after stopping the injection of antibody, thestructure of the surface layer returned to normal appearance. |
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| Keywords: | collagen antibody surface layer knee joint rat |
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