维生素D与肌肉功能

维生素D是调节钙、磷及骨代谢平衡的重要因素,并与多种疾病的发生相关.目前维生素D缺乏已成为全球性的公共健康问题.维生素D缺乏可影响肌肉功能,导致肌力、平衡能力下降,使老年人骨折风险增加.补充维生素D能够改善肌肉功能、减少跌倒及骨折的发生.该文就维生素D的代谢、主要作用机制、维生素D缺乏的原因及后果、维生素D治疗等方面对维生素D与肌肉功能关系的基础及临床知识进行综述.

Vitamin D and Muscle Function

Vitamin D is an important regulator of calcium, phosphorus and bone metabolism and it is related to the development of many diseases. Nowadays, vitaimin D deficiency is a worldwide public health issue. Vitamin D deficiency could impair muscle function, decrease the muscle strength and increase the inci-dence of fracture in elderly people. Supplementation with vitamin D may improve muscle function and reduce the risk for falling. The aim of this review is to summarize the current knowledge from recently published studies on the relationship between vitamin D and muscle function from the perspectives of vitamin D metabo-lism,main function mechanisms, reasons and results of vitamin D deficiency, and vitamin D therapy.